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Welcome Nov 23, 2014
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 N E W S C E N T E R
Updated:  Nov 23, 2014
Comparison of MGuard embolic protection stent with conventional stents in ST-Segment Elevation Myocardial Infarction
MGuard embolic protection stent is associated with superior rates of complete STR, even in patients with longer delays to reperfusion, in comparison with conventional metallic stents.
The Oregon Sudden Unexpected Death Study: Risk stratification for sudden cardiac death
Severe left ventricular dilatation additively increases risk of sudden cardiac death.
Outcomes of mechanical circulatory support in diabetic patients who underwent left ventricular assist devices implantation
Mechanical circulatory support improves diabetic control in advanced heart failure patients.
Effect of transradial access on mortality in patients with non–ST-segment–elevation myocardial infarction
Radial versus femoral access results in reduced complications and mortality in the patient population.
Role of modifiable cardiovascular disease risk factors on mortality risk in high-risk individuals based on CAC
Vascular calcified plaque scores are associated with increased risk for mortality.
Outcomes of amiodarone in patients with atrial fibrillation
Amiodarone + warfarin is associated with significantly increased stroke and systemic embolism risk and a lower time in the therapeutic range.
ACS patients undergoing PCI spent more time in the low acceleration category indicating sedentary behaviour and sleep than stable angina patients
Predictive role of carotid vascular strain in treated hypertension
Decreased carotid strain and strain rate are associated with cardiovascular events in regularly treated hypertensive patients.
Risk prediction by stress myocardial perfusion positron emission tomography in subjects with and without diabetes
Positron emission tomography myocardial perfusion imaging provides incremental risk prediction of cardiac death in both diabetic and non-diabetic subjects.
 LAST 6 DAYS NEWS
Effect of transradial access on mortality in patients with non–ST-segment–elevation myocardial infarction
Radial versus femoral access results in reduced complications and mortality in the patient population.
Role of modifiable cardiovascular disease risk factors on mortality risk in high-risk individuals based on CAC
Vascular calcified plaque scores are associated with increased risk for mortality.
Outcomes of amiodarone in patients with atrial fibrillation
Amiodarone + warfarin is associated with significantly increased stroke and systemic embolism risk and a lower time in the therapeutic range.
ACS patients undergoing PCI spent more time in the low acceleration category indicating sedentary behaviour and sleep than stable angina patients
Predictive role of carotid vascular strain in treated hypertension
Decreased carotid strain and strain rate are associated with cardiovascular events in regularly treated hypertensive patients.
Risk prediction by stress myocardial perfusion positron emission tomography in subjects with and without diabetes
Positron emission tomography myocardial perfusion imaging provides incremental risk prediction of cardiac death in both diabetic and non-diabetic subjects.
JPAD Trial: New blood pressure control target for diabetic patients
140/90 mmHg is a significantly better BP control target for diabetics.
Correlation between glycosylated hemoglobin level with severity of atherosclerotic cardiovascular diseases
Increased HbA1c level is independently associated with the severity of coronary artery diseases.
EXAMINE: Impact of alogliptin on NT-pro-BNP in a post-ACS T2D population
N-Terminal-pro-brain natriuretic peptide decreases following treatment with alogliptin in T2DM patients with recent acute coronary syndromes.
Pooled PROTECT Trials: Mortality risks associated with stent thrombosis with coronary stents
Early and late stent thrombosis are associated with long-term cardiac mortality.
Optimal treatment option for in-stent restenosis
Drug-eluting balloon or Drug-eluting stent markedly better prevented target lesion revascularization than plain old balloon angioplasty, but not MI or mortality in treatment of ISR.
Drug-Eluting Stents versus Bare Metal Stents outcomes in STEMI patients
Compared with BMS, DES use is associated with a significantly lower 30-day mortality, after which there is no difference in mortality between the groups.
Combination of depression and diabetes is associated with short-term risk of death and myocardial infarction among patients undergoing angiography for acute coronary syndrome
Association of endothelial dysfunction, arterial stiffness and inflammation with visual impairment among diabetics
Visual impairment could be predicted by both endothelial function and arterial stiffness with high sensitivity.
Impact of ranolazine in patients with chronic stable angina and diabetes
Ranolazine improves cardiovascular-and diabetes-related healthcare utilization in patients with chronic stable angina and co-morbid diabetes.
Benefits with delayed versus immediate stenting in AMI patients
Delayed stenting improves angiographic outcomes when compared with immediate stenting for acute myocardial infarction.
Protective affect of anticoagulation in transcutaneous aortic valve replacement
There is a trend towards improved survival and stroke rates in anticoagulation patients.
Effect of lesion morphology and location in patient with intermediate stenotic coronary lesions
Lesion location and degree of diameter stenosis affect fractional flow reserve.
Benefits of angiotensin converting enzyme inhibitors in systolic heart failure patients with glomerular filtration rate <30 ml/min/1.73 m2
ACEIs treatment is associated with improved survival in CKD patients with GFR < 30ml/min/1.73m2.
Role of digoxin in modern treatment of heart failure with sinus rhythm
Digoxin is associated with an increased risk of death in chronic HF with sinus rhythm.
ASCEND-HF: Torsemide versus Furosemide in Acute Heart Failure Patients
Minority of patients received torsemide and commonly had indicators of higher risk.
Net atrioventricular compliance: A novel parameter to predict long-term cardiac mortality in mitral stenosis
New Onset Atrial Fibrillation after First-ever Ischemic Stroke in Lund Stroke Register
Prolonged P-wave duration is the strongest predictor of AF incidence in stroke-free population.
Aspirin + Clopidogrel Therapy versus clopidogrel alone following coronary stent implantation in AMI patients
Clopidogrel alone use following coronary stenting does not increase mortality and worsen clinical outcomes when compared to DAP therapy in AMI patients.
ALKK-Registry: Optimal antithrombotic therapy in patients undergoing primary PCI
Gp IIb/IIIa inhibitors improve outcome in patients with primary PCI for STEMI treated with heparin.
Cardiovascular risk during young adulthood in offspring of women with hypertension during pregnancy
Maternal hypertension in pregnancy is associated with increased blood pressure.
CARDIA Study: Nocturnal Blood Pressure in Young Adults and Cognitive Function in Midlife
Less nocturnal SBP dipping and higher nocturnal DBP levels are associated with lower executive function in midlife in healthy young adults.
CARDIA Study: Impact of cumulative blood pressure in early adulthood on cardiac dysfunction during middle age
BP for over 25 years from young adulthood to middle age results in left ventricular systolic and diastolic dysfunction in middle age.
Systematic Review and Meta-Analysis: Impact of sitagliptin on cardiac outcomes
Sitagliptin versus placebo shows no significant benefit on cardiac outcomes.
Time dependent effects Dapagliflozin on cardiovascular safety
Dapagliflozin was not associated with any increased risk of early or late adjudicated cardiovascular events.
BP lowering effect of Empagliflozin in T2DM patients under background antihypertensive treatment
BP reduction with empagliflozin in type 2 diabetes is similar in treatment naïve as in those on one or ≥ 2 antihypertensive agents.
Long-term outcome of acute myocardial infarction with initial low-density lipoprotein cholesterol reduction in the statin era
Impact of exercise training on Ang-II and AGEs in patients with diabetic kidney disease
Exercise reduces angiotensin II and advanced glycation end products in patients with diabetic kidney disease.
Predictive value of ankle-brachial index on central aortic stiffness and its progression
Ankle-brachial index predicts progression of aortic stiffeness.
Vascular endothelial growth factor-C value as a predictive marker of ardiovascular events in patients with arteriosclerotic obliterans
Serum vascular endothelial growth factor-C levels are inversely associated with major adverse cardiovascular events.
Effects of ACE/ARB in patients with marfan syndrome
Angiotensin blockade reduces aortic dilatation in patients with marfan syndrome.
Impact of early discontinuation of fondaparinux in non-invasive treatment of low-risk patients with non-st-elevation acute coronary syndrome
Levels of thrombin-antithrombin, D-dimer and plasmin-antiplasmin as well as their changes do not correlate with recurrence of ischemia.
TRACER Study: Thienopyridine use prior to presentation for acute coronary syndromes and association with safety and efficacy of vorapaxar
In pts with prior thienopyridine use, there was no change in efficacy of vorapaxar and there was no excess in severe bleeding.
Impact of metformin treatment on levels of adiponectin in MI patients
Metformin lowers circulating adiponectin levels in patients with myocardial infarction.
Long term mortality in patients with newly diagnosed diabetes versus known diabetics after ST segment elevation myocardial infarction
Patients with newly diagnosed diabetes have comparable long term mortality with known diabetics after ST segment elevation myocardial infarction.
Impact of optimal therapeutic management on survival in ST-elevation myocardial patients with altered glomerular filtration rate
Optimal therapeutic management lowers long-term mortality irrespective of the the eGFR category.
Association between sulfonylurea use and risk of cardiovascular disease among patients with diabetes
Sulfonylureas use for a long time is associated with a significantly higher risk of developing CHD among women with diabetes.
Stent coverage and neointimal proliferation in bare metal stents postdilated with a paclitaxel-eluting balloon versus everolimus-eluting stents
Both DES and BMS+DEB effectively prevented clinically relevant focal restenosis at 6-month.
Coronary atheroma regression in diabetic individuals with statins
High-intensity statin therapy alters the natural history of diabetic coronary atherosclerosis which leads to regression of disease in diabetic and nondiabetic patients.
Bleeding risk in the era of drug-eluting stent
Synergistic action of prolonged dual antiplatelet therapy and oral anticoagulation increases the risk of major bleeding after primary PCI.
Impact of gestational diabetes on the stereoselective pharmacokinetics and placental distribution of metoprolol and its metabolites in parturients
Well-controlled GDM does not have any affect on the activity of CYP2D6 and CYP3A involved in metoprolol metabolism.
Association of renin-angiotensin blockade with risk of hospitalization for community acquired pneumonia in the elderly
Medications that block the renin angiotensin system leads to a small absolute reduction in the 90 day risk of hospitalization with pneumonia.
Impact of compound danshen dripping pill pretreatment on contrast-induced nephropathy in ACS patients undergoing PCI
Compound danshen dripping pill pretreatment can decrease contrast-induced nephropathy occurrence in patients undergoing PCI.
 REVIEWS
Decompensated heart failure
Resistant Hypertension: A challenge for primary care clinicians and specialists
Safety outcomes of aortic valve replacement in aortic stenosis
Fixed-Drug Combinations for an Effective, Treatment Adherence led BP control
Biodegradable Stents or Scaffolds over DESs
Controversies in the significance of Fractional Flow Reserve Measurement for the Assessment of Coronary Artery Disease
Making a Wise Choice for Enhancing the Success of an unstable PCI Era
Risk Management and New Technologies in Atrial Fibrillation Ablation as the First-line therapy for a Lasting Cure
Chronic Kidney Disease as a New Therapeutic Target in the DES, Valvular and STEMI Era
Prognosis of Hypertrophic Cardiomyopathy
Newer oral anticoagulation therapy for patients with atrial fibrillation
A Coronary Perforation Complicating a PCI is No More Feared: The Dual Catheter rather than Single Catheter Access Technique for a dauntless cardiac intervention
  More..

 INDUSTRY NEWS

The WATCHMAN™ Left Atrial Appendage Closure Device receives favorable vote by FDA Advisory Committee Panel

FDA clears 150 cm Length Arrow® GPSCath® Balloon Dilatation Catheters

FDA approves Sorin Group's Solo Smart™ Aortic Pericardial Heart Valve
  More..

 INTERESTING  CASES
 
A 81 year old male patient with a history of hypertension, dyslipidemia, and smoking, presented with a history of chest pain with minimal efforts of two days duration.
Good angiographic result with a TIMI 3 flow was attained. The crush technique was the first choice in the treatment of complex bifurcation lesion of left main.
More..

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Baseline characteristics and treatment of patients in Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)

 
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