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Welcome Jul 25, 2014
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 N E W S C E N T E R
Updated:  Jul 25, 2014
HEAT-PPCI: Unfractionated heparin versus bivalirudin in the setting of primary percutaneous coronary intervention
When compared to bivalirudin, heparin reduces the incidence of major adverse ischaemic events in the setting of PPCI.
Coronary artery disease in adult survivors of childhood Hodgkin lymphoma
CAD, identified by coronary computed tomography angiography, in a substantial percentage of survivors of Hodgkin lymphoma may be an effective screening modality for this population.
CLARIFY registry: Inadequate heart rate control despite widespread use of beta-blockers in outpatients with stable CAD
Patients with angina, previous myocardial infarction, heart failure, and hypertension were more frequently on beta-blockers, while those with PAD and asthma/COPD less frequently used this drug.
Virtual histology intravascular ultrasound analysis of correlation between neutrophil-to-lymphocyte ratio and plaque components in CAD patients
CAD patients with high NLR versus low NLR, had more vulnerable plaque components.
Correlation of pentraxin 3 with coronary atherosclerosis and metabolic factors
Pentraxin 3 may have an atheroprotective role and may serve as a simple biomarker, like adiponectin.
 LAST 6 DAYS NEWS
Impact of side branch predilatation on outcomes in coronary bifurcation lesions treated by the provisional approach
Side branch predilatation before main vessel stenting may be associated with an increased risk of repeat revascularization in patients with true nonleft main bifurcation treated by the provisional approach.
Ventricular cardiac dyssynchrony in patients with repaired tetralogy of Fallot
Patients with tetralogy of Fallot have intra- and inter-ventricular dyssynchrony, which can be quantified from standard cine cardiac magnetic resonance.
Assessment of carotid atherosclerosis, intraplaque neovascularization, and plaque ulceration in asymptomatic patients with diabetes mellitus
Prevalence of subclinical carotid atherosclerosis in patients with DM is high.
PROSPECT Study: Correlation of C-reactive protein levels to instability of untreated vulnerable coronary plaques
Higher rates of NCL-related MACE may reflect greater instability of high-risk NCLs, rather than a larger burden of such lesions in post–acute coronary syndrome patients with very elevated CRP levels.
Predicting mortality in patients receiving cardiac resynchronization therapy based on pre-implantation risk factors
EAARN score can be useful to stratify the prognosis of cardiac resynchronization therapy patients.
SHIFT post hoc analysis: Efficacy and safety of ivabradine in chronic systolic heart failure patients, according to tertiles of blood pressure
Efficacy and safety of ivabradine is not affected by systolic blood pressure.
FIGURE-OUT study: Diagnostic value of coronary CT angiography versus invasive coronary angiography and intravascular ultrasound in patients with intermediate coronary artery stenosis
Compared with invasive methods, coronary computed tomographic angiography presents overestimation in assessing lesion severity and lower diagnostic performance in assessing ischaemia.
Predictive power of waist-to-height ratio versus body mass index and waist circumference for identifying cardiometabolic risk in non-obese individuals
Waist-to-height ratio is an appropriate index for identifying cardiometabolic risk in individuals with normal body mass index and waist circumference.
Correlation between heart failure and risk of diabetes
Severity of heart failure is associated with a stepwise increased risk of developing diabetes.
Association of below-knee arterial calcification with receptor activator of nuclear factor kappa B ligand, osteoprotegerin and neuropathy in type 2 diabetes
Below knee arterial calcification severity was correlated with peripheral neuropathy severity and with several usual cardio-vascular risk factors, but not with serum RANKL level.
Predicting mortality in patients referred for coronary angiography and symptoms of heart failure with preserved ejection fraction
C-reactive protein is an independent and strong predictor of mortality in patients with heart failure with preserved ejection fraction.
I-Preserve trial: Association between heart rate and outcomes in patients with heart failure and preserved ejection fraction
With each standard deviation (12.4 bpm) increase in heart rate, the risk of cardiovascular death or heart failure hospitalization increases by 13%.
Dallas lesion set is an effective treatment in patients with long-standing persistent atrial fibrillation
Dallas lesion set results in significant improvement in LA volume and function after restoration of sinus rhythm.
Efficacy of beta-blocker therapy for secondary prevention in STEMI patients
Beta-blocker therapy at discharge improves survival in STEMI patients treated with primary PCI.
Correlation of HOMA-IR, fasting insulin and fasting glucose with coronary heart disease mortality in nondiabetic men
The independent risk factors for CHD mortality are insulin resistance and fasting serum insulin, but not fasting plasma glucose.
Tricuspid annuloplasty versus tricuspid valve replacement in patients with functional tricuspid regurgitation
Tricuspid annuloplasty should be considered as a treatment of choice for patients with severe FTR as TVR is associated with long-term cardiac death and valve-related events.
Yield of stress testing in non-elderly, obese, sedentary patients with dyspnoea on exertion
Obese sedentary patients with dyspnoea on exertion who are at low risk for coronary artery disease by clinical criteria have a very low prevalence of coronary artery disease.
ROCKET AF prespecified secondary analysis: Rivaroxaban versus warfarin among elderly patients with nonvalvular atrial fibrillation
Rivaroxaban can be used as an alternative for the elderly, as its efficacy and safety relative to warfarin does not differ with age.
24 hour variation in blood pressure and arterial stiffness in chronic kidney disease
In CKD, activation of the ET system seems to contribute not only to raised BP but also to the loss of BP dipping.
Toranomon Hospital Health Management Center Study 18 (TOPICS 18): Role of body mass index history in predicting risk of the development of hypertension
An elevated body mass index at the baseline examination weakenes the favorable influence of a low body mass index in early adulthood on developing hypertension.
Outcomes of patients with non-ST-segment elevation acute coronary syndromes with no angiographically obstructive coronary artery disease
Rate of major cardiac events is lower in patients with non-obstructive CAD versus those with obstructive CAD, but is not negligible.
The PROFIT-J Study: Macrovascular outcomes of pioglitazone therapy in patients with type 2 diabetes mellitus at high risk of stroke
Pioglitazone is associated with immediate and effective improvements in glycemic control, diastolic blood pressure and lipid profiles.
Correlation between the Lipoprotein-Associated Phospholipase A2 Activity and the progression of subclinical atherosclerosis
Lipoprotein-associated phospholipase A2 level is associated with the progression of subclinical atherosclerosis in men.
Impact of Liraglutide on carotid intima-media thickness in patients with type 2 diabetes
Liraglutide decreases carotid intima-media thickness from 1.19 ± 0.47 to 0.94 ± 0.21 mm in eight months.
Correlation between a low ankle brachial index and all-cause death and cardiovascular events in subjects with and without diabetes
Low ankle brachial index is significantly and cross-sectionally associated with conventional risk factors.
Correlation between endogenous complement inhibitor and myocardial salvage in patients with myocardial infarction
Salvage index and final infarct size did not correlate with plasma levels of MAp44.
Relationship between plasma adiponectin levels and aortic stiffness in patients with acute ST-segment elevation myocardial infarction
Plasma adiponectin concentrations are strongly associated with aortic stiffness.
The Seattle Post Myocardial Infarction Model (SPIM): predicting mortality after acute myocardial infarction with left ventricular dysfunction
SPIM score is a powerful predictor of outcomes after myocardial infarction with left ventricular dysfunction.
Correlation between exercise capacity and all-cause mortality in male veterans with hypertension aged ≥70 years
Exercise capacity is associated with lower mortality risk in elderly men with hypertension
Role of brachial-ankle pulse wave velocity in predicting mortality among patients with acute stroke
Brachial-ankle pulse wave velocity is a strong predictor for mortality in patients with acute stroke.
 REVIEWS
Decompensated heart failure
Resistant Hypertension: A challenge for primary care clinicians and specialists
Safety outcomes of aortic valve replacement in aortic stenosis
Fixed-Drug Combinations for an Effective, Treatment Adherence led BP control
Biodegradable Stents or Scaffolds over DESs
Controversies in the significance of Fractional Flow Reserve Measurement for the Assessment of Coronary Artery Disease
Making a Wise Choice for Enhancing the Success of an unstable PCI Era
Risk Management and New Technologies in Atrial Fibrillation Ablation as the First-line therapy for a Lasting Cure
Chronic Kidney Disease as a New Therapeutic Target in the DES, Valvular and STEMI Era
Prognosis of Hypertrophic Cardiomyopathy
Newer oral anticoagulation therapy for patients with atrial fibrillation
A Coronary Perforation Complicating a PCI is No More Feared: The Dual Catheter rather than Single Catheter Access Technique for a dauntless cardiac intervention
  More..

 INDUSTRY NEWS

Medtronic announces the positive preliminary results of Micra(TM) Transcatheter Pacing System, the World's Smallest Cardiac Pacemaker

FDA issues clarification on Sildenafil use in PAH children in the right circumstances

REBEL™ Platinum Chromium Coronary Stent System of Boston Scientific receives CE Mark Approval
  More..

 INTERESTING  CASES
 
A 81 year old male patient with a history of hypertension, dyslipidemia, and smoking, presented with a history of chest pain with minimal efforts of two days duration.
Good angiographic result with a TIMI 3 flow was attained. The crush technique was the first choice in the treatment of complex bifurcation lesion of left main.
More..

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Baseline characteristics and treatment of patients in Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)

 
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