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Welcome Oct 24, 2014
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 N E W S C E N T E R
Updated:  Oct 24, 2014
Determinants of weight loss in overweight and obese adults
Eating behavior traits and sleep may act together to influence the outcome of weight-loss programs.
Efficacy of statins for preventing contrast-induced acute kidney injury in patients undergoing coronary angiography
Pretreatment with high-dose statins versus low-dose statins or placebo, reduces the incidence of CIAKI, in patients undergoing coronary angiography.
Detecting expression of platelet microRNA among diabetic patients with or without ischemic stroke
Low platelet and plasma miR-223 and miR-146a expression are risk factor for ischemic stroke among diabetics.
Risk factor in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention
Lower serum triglyceride level is a risk factor for in-hospital and late major adverse events in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
Outcomes of Bare-Metal vs. Drug-Eluting Stents in patients with atrial fibrillation undergoing percutaneous coronary intervention
DES use is associated with outcomes comparable to those with BMS without excess bleeding complications.
One-year clinical outcomes of everolimus- versus sirolimus-eluting stents in patients with acute myocardial infarction
Second-generation drug-eluting stent EES has at least comparable or even better safety and efficacy profiles when compared with SES.
Sirolimus systemic exposure and bioresorbable polymer properties of Ultimaster DES in CAD patients
Ultimaster stent leads to almost non-detectable sirolimus in blood after 28 days.
Correlation between endothelial function, cardiovascular risk, and metabolic syndrome in patients with non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease in association with non-alcoholic fatty liver disease, further increases the risk of cardiovascular events.
DEFINITION Study: Impact of bifurcation lesions complexity treated with drug-eluting stents
2-stent techniques elicits a lower cardiac death and in-hospital MACE rate for complex lesions but higher rates of in-hospital ST and revascularization at 1 year for simple lesions.
Correlation between hypoglycaemia and QT interval prolongation in T1DM
Insulin induced hypoglycaemia may cause QTc prolongation in patients with T1DM.
Association of levels of irisin with cardio-metabolic variables and insulin sensitivity
High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in nondiabetic adults.
Impact of liraglutide + calorie-restricted diet on lipoprotein profile and CVD risk in overweight/obese prediabetics
Liraglutide therapy plus modest calorie restriction leads to improvement in multiple aspects of lipid/lipoprotein metabolism associated with increased cardiovascular disease (CVD) risk.
Computerized algorithm versus conventional approach for glycemic control in patients undergoing cardiopulmonary bypass
Early computer-based insulin therapy allows better achievement of normoglycemia in patients undergoing major cardiac surgery with the use of blood cardioplegia.
Outcomes of ivabradine treatment in patients with chronic heart failure
Ivabradine treatment for a period over 4 months effectively reduces HR and symptoms in CHF patients.
Correlation between epicardial adipose tissue inflammation and vitamin D deficiency
Epicardial adipose tissue inflammation is related to vitamin D deficiency in patients affected by coronary artery disease.
Association of abdominal fat distribution with atherosclerotic changes in the carotid artery
Total fat area may be considered as a valuable measure of atherosclerotic changes.
The Basque Country Prospective Complications and Mortality Study risk engine (BASCORE)
This validated population-derived model could predict 5-year fatal/non-fatal CHD and CVD risk in patients with newly diagnosed T2DM.
Underlying mechanism by which thiazolidinediones prevent the formation and progression of atherosclerosis and restenosis following percutaneous coronary intervention
Pioglitazone modulates the proliferation and apoptosis of vascular smooth muscle cells via peroxisome proliferators-activated receptor-gamma.
Linking diabetes mellitus to platelet dysfunction in patients with ST-elevation myocardial infarction
Mean platelet volume has good prognostic value for in-hospital and late mortality among both diabetics and non-diabetics.
Cardiometabolic profile in metabolically healthy obesity and metabolically abnormal obesity
Cardiometabolic risk factors and inflammation in adipose tissue are increased in obese subjects classified as metabolically healthy.
Lipid Profiling for studying the therapeutic effects of metformin and glipizide in T2DM patients with coronary artery disease
Therapeutic effects of metformin and glipizide are different in patients with type 2 diabetes and coronary artery disease and are comparable with their different long-term effects on cardiovascular outcomes.
Correlation between meat intake and indicators of insulin resistance and endothelial function in women
Increased red meat intake is associated with high concentrations of plasma endothelial dysfunction biomarkers in women.
Swedish Heart Failure Registry: Correlation of QRS prolongation and left bundle branch block with age
With increasing age, both left bundle branch block and intraventricular conduction delay are more common.
Significance of left ventricular apical–basal muscle bundle in patients with hypertrophic cardiomyopathy
Apical–basal muscle bundles may represent an additional morphologic marker for HCM diagnosis in genotype-positive status.
Correlation between serum lipoprotein and cardiometabolic risk in middle-aged adults
Low "quotient" Lp(a) concentration mediates autoimmune activation and independently predicts cardiometabolic risk.
Age-related results from the ADDITIONS study
Ivabradine in combination with beta-blocker reduces symptoms and improves quality of life in elderly patients with stable angina pectoris.
Changes in 24 h ambulatory blood pressure and effects of angiotensin II receptor blockade during hypobaric hypoxia
Ambulatory blood pressure increases progressively with increasing altitude, remaining elevated after 3 weeks.
Preventing metabolic disorders with telmisartan and indapamide in a high-normal blood pressure population
Intervention with telmisartan and indapamide for high-normal blood pressure appeared to be feasible.
Efficacy and safety of triple therapy vs dual anti hypertensive therapy of ramipril, telmisartan and hydrochlorothiazide in stage 2 hypertensive patients
All three medications were of equal efficacy in patients with stage 2 hypertension without co morbid conditions.
Correlation between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction
Risk of acute coronary syndrome and HF hospitalization is increased in patients with HF-REF and ongoing angina.
Correlation between resistance exercise and cardiovascular disease risk in women
Resistance exercise may be particularly beneficial to independently improve cardiovascular disease risk profiles in women with normal weight.
Impact of paravalvular regurgitation following transcatheter aortic valve replacement
Both mild and moderate/severe paravalvular regurgitation predict higher 1-year mortality.
Prognostic value of restenosis in patients undergoing routine control angiography after coronary stenting
Presence of restenosis at follow-up angiography after coronary stenting is predictive of 4-year mortality.
MAGGIC: Heart failure in younger patients
Younger patients with heart failure have more severe left ventricular dysfunction and less severe symptoms.
Impact of left ventricular assist devices implantation on diabetic parameters in heart failure patients
Mechanical circulatory support improves diabetic control in patients with advanced heart failure.
Benefits of implantable cardioverter-defibrillator treatment in patients responding to cardiac resynchronization therapy
Super-responders to cardiac resynchronization therapy remain at risk for ventricular arrhythmias and benefit from defibrillator treatment.
Left atrial function in patients with heart failure with preserved ejection fraction
Left atrial dysfunction may be a marker of severity and play a pathophysiological role in HFpEF.
Predictive value of left atrial volume on abnormal exercise LV filling pressure
Left atrial volume predicts abnormal exercise left ventricular filling pressure.
Assessment of a failing Fontan circuit in patients after the Fontan procedure
Serial measurements of MR-proADM levels may help in identify patients at risk for a failing Fontan circulation especially when exceeding 0.520nmol/L.
Irish Longitudinal Study on Ageing (TILDA): Normative changes in phasic orthostatic blood pressure with aging
There exist significant age related differences in the time course of postural BP responses with abnormal responses which takes longer than 30 seconds to stabilize.
Insights from the ARISTOTLE Trial: Growth Differentiation Factor 15 for risk assessment in patients with atrial fibrillation
GDF-15 is a risk factor for major bleeding, mortality and stroke in atrial fibrillation.
Association of alternatively spliced tissue factor with neovascularization
Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling.
The Cardiovascular Health Study: Correlation between circulating omega-6 polyunsaturated fatty acids and mortality
High circulating linoleic acid, but not other n-6 PUFA, associated inversely with total and CHD mortality in older adults.
Outcomes of empagliflozin treatment in patients with type 2 diabetes and hypertension
Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension.
Diabetes Prevention Program: Effects of Weight Loss, Weight Cycling, and Weight Loss Maintenance on Diabetes Incidence and Change in Cardiometabolic Traits
Two-year weight loss was the strongest predictor of reduced diabetes risk and improvements in cardiometabolic traits.
The Bogalusa Heart Study: Effect of excessive adiposity and elevated blood pressure from childhood on left ventricular remodeling patterns in adulthood
Adverse influence of excessive adiposity and elevated BP levels on LVH begins in childhood.
IN.PACT DEEP Randomized Trial: Drug-Eluting Balloon Versus Standard Balloon Angioplasty for Infrapopliteal Arterial Revascularization in Critical Limb Ischemia
Amphirion drug-eluting balloons and PTA exhibit comparable efficacy.
ARISTOTLE Trial: Outcomes of amiodarone in patients with atrial fibrillation
Amiodarone when used with warfarin is associated with significantly increased stroke and systemic embolism risk and a lower time in the therapeutic range.
Diabetes Heart Study: Contributors to Mortality in High-Risk Diabetic Patients
Vascular calcified plaque scores are associated with increased risk for mortality.
Obstructive sleep apnea in T1DM patients with cardiovascular autonomic neuropathy
Cardiovascular autonomic neuropathy contributes to sleep apnea in young and lean type 1 diabetes mellitus patients.
Correlation between asymptomatic atrial fibrillation episodes and abnormalities of the autonomic nervous system among diabetics
Autonomic dysfunction is associated with brief episodes of atrial fibrillation in type 2 diabetes.
HONEST: Correlation between Home Blood Pressure and Cardiovascular risk in patients during antihypertensive therapy
Morning home blood pressure should be controlled to <145 mm Hg, even among patients with controlled clinic blood pressure.
Office blood pressure and 24-hour ambulatory blood pressure decrease with antihypertensive treatment
There was a disproportionally greater decrease in systolic office BP than in ambulatory blood pressure.
Differences between conventional and ambulatory daytime blood pressure values
The relation between daytime ambulatory and conventional BP strongly vary according to age.
Regadenoson Stress Magnetic Resonance Imaging for risk stratification in patients with known or suspected coronary artery disease
Regadenoson cardiac magnetic resonance myocardial perfusion imaging provides robust risk stratification in patients with clinical suspicion of myocardial ischemia.
Decompensated heart failure
Resistant Hypertension: A challenge for primary care clinicians and specialists
Safety outcomes of aortic valve replacement in aortic stenosis
Fixed-Drug Combinations for an Effective, Treatment Adherence led BP control
Biodegradable Stents or Scaffolds over DESs
Controversies in the significance of Fractional Flow Reserve Measurement for the Assessment of Coronary Artery Disease
Making a Wise Choice for Enhancing the Success of an unstable PCI Era
Risk Management and New Technologies in Atrial Fibrillation Ablation as the First-line therapy for a Lasting Cure
Chronic Kidney Disease as a New Therapeutic Target in the DES, Valvular and STEMI Era
Prognosis of Hypertrophic Cardiomyopathy
Newer oral anticoagulation therapy for patients with atrial fibrillation
A Coronary Perforation Complicating a PCI is No More Feared: The Dual Catheter rather than Single Catheter Access Technique for a dauntless cardiac intervention


The WATCHMAN™ Left Atrial Appendage Closure Device receives favorable vote by FDA Advisory Committee Panel

FDA clears 150 cm Length Arrow® GPSCath® Balloon Dilatation Catheters

FDA approves Sorin Group's Solo Smart™ Aortic Pericardial Heart Valve

A 81 year old male patient with a history of hypertension, dyslipidemia, and smoking, presented with a history of chest pain with minimal efforts of two days duration.
Good angiographic result with a TIMI 3 flow was attained. The crush technique was the first choice in the treatment of complex bifurcation lesion of left main.

AHA 2014
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Baseline characteristics and treatment of patients in Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)

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